Photosensitizer-5
Photosensitizer-5 is a photosensitizer. Photosensitizer-5 has cytotoxicity against HeLa and HepG2 cells, with IC50 values of 10.4 nM and 6.9 nM, respectively. Photosensitizer-5 can lead to lipid peroxidation and induces cell death through an iron-independent ferroptosis-like pathway. Photosensitizer-5 shows anti-tumor activity in HeLa tumor-bearing mice[1].
Product Specifications
UNSPSC
12352005
Target
Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/photosensitizer-5.html
Smiles
IC1=C(C2=CC=C(OC)C=C2)N3C(N=C4C(C5=CC=CC=C5)=C6CCC7=C(C=CC(OC)=C7)C6=[N+]4[B-](F)3F)=C1C8=CN=CC=C8
Molecular Formula
C35H26BF2IN4O2
Molecular Weight
710.32
References & Citations
[1]Liu C, et al. Synthesis and Photodynamic Activities of Pyridine- or Pyridinium-Substituted Aza-BODIPY Photosensitizers. J Med Chem. 2024 Aug 21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Browse additional items from our catalog
Recombinant Arabidopsis thaliana Glutamate receptor 1.2 (GLR1.2) , partial
