Photosensitizer-5
Photosensitizer-5 is a photosensitizer. Photosensitizer-5 has cytotoxicity against HeLa and HepG2 cells, with IC50 values of 10.4 nM and 6.9 nM, respectively. Photosensitizer-5 can lead to lipid peroxidation and induces cell death through an iron-independent ferroptosis-like pathway. Photosensitizer-5 shows anti-tumor activity in HeLa tumor-bearing mice[1].
Product Specifications
UNSPSC
12352005
Target
Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/photosensitizer-5.html
Smiles
IC1=C(C2=CC=C(OC)C=C2)N3C(N=C4C(C5=CC=CC=C5)=C6CCC7=C(C=CC(OC)=C7)C6=[N+]4[B-](F)3F)=C1C8=CN=CC=C8
Molecular Formula
C35H26BF2IN4O2
Molecular Weight
710.32
References & Citations
[1]Liu C, et al. Synthesis and Photodynamic Activities of Pyridine- or Pyridinium-Substituted Aza-BODIPY Photosensitizers. J Med Chem. 2024 Aug 21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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