α-Conotoxin RgIA
Product Specifications
CAS Number
876728-23-3
UNSPSC Description
α-Conotoxin RgIA (α-RgIA) is a specific α9α10 nAChR antagonist. α-Conotoxin RgIA can be obtained from Conus regius venom. α-Conotoxin RgIA can be used in the study of neurological diseases[1].
Target Antigen
nAChR
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.44
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CN)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1[C@H](C(N[C@H]2CCCNC(N)=N)=O)CCC1)=O)CC(O)=O)=O)CO)=O)CSSC[C@H](NC3=O)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)CSSC[C@H](NC2=O)C(N[C@H](C(N[C@H](C(N[C@H]3CCCNC(N)=N)=O)CC4=CC=C(O)C=C4)=O)CCCNC(N)=N)=O
Molecular Weight
1570.80
References & Citations
[1]Ellison M, et al. Alpha-RgIA: a novel conotoxin that specifically and potently blocks the alpha9alpha10 nAChR. Biochemistry. 2006 Feb 7;45(5):1511-7.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Clinical Information
No Development Reported
Available Sizes
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