Tulobuterol (hydrochloride)

Tulobuterol hydrochloride (C-78) is a long-acting β2-adrenoceptor agonist, which reduces the frequency of exacerbations of chronic obstructive pulmonary disease and bronchial asthma. Tulobuterol hydrochloride is also a sympathomimetic agent used as a transdermal patch, increases normal diaphragm muscle strength[1]. Tulobuterol hydrochloride inhibit rhinovirus replication and modulate airway inflammation[2].

Product Specifications

CAS Number

[56776-01-3]

Product Name Alternative

C-78

UNSPSC

12352005

Hazard Statement

H302

Target

Adrenergic Receptor; Antibiotic; Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection; GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-anti-virus

Field of Research

Infection; Endocrinology; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Tulobuterol_hydrochloride.html

Purity

99.83

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

CC(C)(NCC(O)C1=CC=CC=C1Cl)C.Cl

Molecular Formula

C12H19Cl2NO

Molecular Weight

264.19

Precautions

H302

References & Citations

[1]Shindoh C, et al. Tulobuterol patch maintains diaphragm muscle contractility for over twenty-four hours in a mouse model of sepsis. Tohoku J Exp Med. 2009 Aug;218 (4) :271-8.|[2]Yamaya M, et al. Tulobuterol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells. Physiol Rep. 2013 Aug;1 (3) :e00041.