Coagulation Factor II/F2, Mouse (HEK293, His)

Coagulation Factor II/F2, also known as thrombin, functions as a pivotal serine protease. Its enzymatic action involves cleaving bonds after Arg and Lys residues, facilitating the conversion of fibrinogen to fibrin. Thrombin additionally activates key factors like V, VII, VIII, XIII, and, in conjunction with thrombomodulin, protein C. Beyond blood homeostasis, thrombin plays a role in inflammation and the complex dynamics of wound healing. Coagulation Factor II/F2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Coagulation Factor II/F2 protein, expressed by HEK293 , with C-His labeled tag. The total length of Coagulation Factor II/F2 Protein, Mouse (HEK293, His) is 594 a.a., with molecular weight of ~85 kDa.

QHVFLAPQQA LSLLQRVRRA NSGFLEELRK GNLERECVEE QCSYEEAFEA LESPQDTDVF WAKYTVCDSV RKPRETFMDC LEGRCAMDLG VNYLGTVNVT HTGIQCQLWR SRYPHKPEIN STTHPGADLK ENFCRNPDSS TTGPWCYTTD PTVRREECSV PVCGQEGRTT VVMTPRSGGS KDNLSPPLGQ CLTERGRLYQ GNLAVTTLGS PCLPWNSLPA KTLSKYQDFD PEVKLVENFC RNPDWDEEGA WCYVAGQPGD FEYCNLNYCE EAVGEENYDV DESIAGRTTD AEFHTFFNEK TFGLGEADCG LRPLFEKKSL KDTTEKELLD SYIDGRIVEG WDAEKGIAPW QVMLFRKSPQ ELLCGASLIS DRWVLTAAHC ILYPPWDKNF TENDLLVRIG KHSRTRYERN VEKISMLEKI YVHPRYNWRE NLDRDIALLK LKKPVPFSDY IHPVCLPDKQ TVTSLLRAGY KGRVTGWGNL RETWTTNINE IQPSVLQVVN LPIVERPVCK ASTRIRITDN MFCAGFKVND TKRGDACEGD SGGPFVMKSP FNNRWYQMGI VSWGEGCDRK GKYGFYTHVF RLKRWIQKVI DQFG