Ac-Arg-Gly-Lys-AMC
Ac-Arg-Gly-Lys-AMC is a fluorogenic substrate for the determination of protease activity. Ac-Arg-Gly-Lys-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC) . AMC is fluorescent under UV light and can emit a fluorescent signal[1].
Product Specifications
CAS Number
660846-99-1
UNSPSC
12352209
Target
Fluorescent Dye
Type
Peptides
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ac-arg-gly-lys-amc.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=C(NC([C@H](CCCCN)NC(CNC([C@@H](NC(C)=O)CCCNC(N)=N)=O)=O)=O)C=C1O2)=CC2=O
Molecular Formula
C26H38N8O6
Molecular Weight
558.63
References & Citations
[1]Noonepalle S, et, al. Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models. J Med Chem. 2020 Sep 24;63 (18) :10246-10262.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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