MTOR inhibitor-1

MTOR inhibitor-1 (Compound C-4) is an ATP-Competitive mTOR inhibitor which can suppress cells proliferation and inducing autophagy[1].

Product Specifications

CAS Number

[468747-17-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Autophagy; mTOR

Type

Reference compound

Related Pathways

Autophagy; PI3K/Akt/mTOR

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mTOR_inhibitor-1.html

Concentration

10mM

Purity

98.82

Solubility

DMSO : 83.33 mg/mL (ultrasonic)

Smiles

O=C(N/N=C(C1=CC=C(O)C=C1O)\C)C2=CC=C(C)C(Br)=C2

Molecular Formula

C16H15BrN2O3

Molecular Weight

363.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Liu J, et al. In Silico Discovery of a Small Molecule Suppressing Lung Carcinoma A549 Cells Proliferation and Inducing Autophagy via mTOR Pathway Inhibition. Mol Pharm. 2018 Nov 5;15 (11) :5427-5436.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-12323AF488 0.1 mL

Mouse Monoclonal Galectin-4 Antibody (MM0300-1D12) [Alexa Fluor 488]

Ask

View Details

H2035-25A 50 µg

Hexokinase 1 (Hexokinase-1, Hexokinase Type I, HEX1, HK I, HKI, HK1, HXK1, Brain Form Hexokinase) discontinued

Ask

View Details

PVT54578 2 µg

pLV3-U6-ATP23-sgRNA1-CAS9-mCherry-Puro Plasmid

Ask

View Details

A19335-10mM-D 10 mM x 1mL in DMSO

Inarigivir soproxil 10mM * 1mL in DMSO

Ask

View Details