CARM1/HDAC2-IN-1
Product Specifications
UNSPSC Description
CARM1/HDAC2-IN-1 (compound CH-1) is a dual inhibitor against CARM1 and HDAC2, with IC50 values of 3.71 nM and 4.07 nM, respectively. CARM1/HDAC2-IN-1 possesses antitumor activity[1].
Target Antigen
HDAC; Histone Methyltransferase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/carm1-hdac2-in-1.html
Solubility
10 mM in DMSO
Smiles
CNCCNCC1=CC=CC(C2=NC(NC3=CC(OCCCCCCC(NO)=O)=CC=C3)=C(C(C4=C5C=CNC5=NC=C4)=N2)C)=C1
Molecular Weight
622.76
References & Citations
[1]Liang S, et al. Discovery and biological evaluation of novel CARM1/HDAC2 dual-targeting inhibitors with anti-prostate cancer agents. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2241118.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157388/CARM1-HDAC2-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157388/
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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