Pep2-8 (TFA)
Pep2-8 is a peptide which has enhanced the antagonistic activity of proprotein convertase subtilin/ kexin 9 type (PCSK9) [1].
Product Specifications
UNSPSC
12352209
Target
PCSK9
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pep2-8-tfa.html
Purity
98.78
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H](C(N)=O)C(C)C)[C@@H](NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@H](CO)NC([C@@]([C@H](O)C)([H])NC([C@@H](NC([C@H](C(C)C)NC([C@H]([C@H](O)C)NC(C)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O)CC4=CC=C(O)C=C4)=O)=O)=O)CC5=CNC6=CC=CC=C56.xOC(C(F)(F)F)=O
Molecular Formula
C83H110N16O24.xC2HF3O2
Molecular Weight
1715.85 (free base)
References & Citations
[1]Lammi C, et al. Biological Characterization of Computationally Designed Analogs of peptide TVFTSWEEYLDWV (Pep2-8) with Increased PCSK9 Antagonistic Activity. Sci Rep. 2019 Feb 20;9 (1) :2343.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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