SDH-IN-16

SDH-IN-16 (compound 5aa) is a potent inhibitor of Succinate Dehydrogenase, with the IC50 of 1.62 μM. SDH-IN-16 displays a broad spectrum of antifungal activity against F. graminearum, B. cinerea, S. sclerotiorum, and R. solani, with the corresponding EC50 values of 0.12, 4.48, 0.33, and 0.15 μg/mL, respectively[1].

Product Specifications

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sdh-in-16.html

Smiles

ClC1=C(N2N=C(C(NNC3=CC=C(Cl)C=C3)=O)C=C2C)C=CC=C1

Molecular Formula

C17H14Cl2N4O

Molecular Weight

361.23

References & Citations

[1]Yiliang Chen, et al. Design, Synthesis, and Antifungal Evaluation of Diverse Heterocyclic Hydrazide Derivatives as Potential Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2024 May 28.