Isoreserpiline

Isoreserpiline is an orally active and BBB-penetrable indole alkaloids with antibacterial and antipsychotic activity. Isoreserpiline is even more effective when used in combination with antibiotics and inhibits the activity of bacterial efflux pumps. Isoreserpiline improves Amphetamine-induced hyperactivity in mice[1][2] .

Product Specifications

CAS Number

[572-67-8]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/isoreserpiline.html

Smiles

COC(C1=CO[C@@H](C)[C@]2([H])CN3CCC(C4=CC(OC)=C(OC)C=C4N5)=C5[C@]3([H])C[C@]12[H])=O

Molecular Formula

C23H28N2O5

Molecular Weight

412.48

References & Citations

[1]Dwivedi GR, et al. Synergy Potential of Indole Alkaloids and Its Derivative against Drug-resistant Escherichia coli. Chem Biol Drug Des. 2015 Dec;86 (6) :1471-81. |[2]Gupta S, et al. Bioactivity guided isolation of antipsychotic constituents from the leaves of Rauwolfia tetraphylla L. Fitoterapia. 2012 Sep;83 (6) :1092-9.