Recombinant Mouse Angiopoietin-like protein 8 (Angptl8)
Product Specifications
Product Name Alternative
Betatrophin (Lipasin) (Refeeding-induced fat and liver protein) (Gm6484) (Rifl)
Abbreviation
Recombinant Mouse Angptl8 protein
Gene Name
Angptl8
UniProt
Q8R1L8
Expression Region
16-198aa
Organism
Mus musculus (Mouse)
Target Sequence
VRPAPVAPLGGPEPAQYEELTLLFHGALQLGQALNGVYRATEARLTEAGHSLGLYDRALEFLGTEVRQGQDATQELRTSLSEIQVEEDALHLRAEATARSLGEVARAQQALRDTVRRLQVQLRGAWLGQAHQEFETLKARADKQSHLLWALTGHVQRQQREMAEQQQWLRQIQQRLHTAALPA
Tag
N-terminal 10xHis-tagged
Type
In Stock Protein
Source
Baculovirus
Field of Research
Cell Biology
Relevance
Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state. According to a report, may act by promoting ANGPTL3 cleavage . According to another study, not required for cleavage of ANGPTL3.
Endotoxin
Not test
Purity
Greater than 85% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight
23.0 kDa
References & Citations
"Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism." Ren G., Kim J.Y., Smas C.M. Am. J. Physiol. 303:E334-E351 (2012)
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Product MSDS
https://www.cusabio.com/msds/12926639/
Protein Length
Full Length of Mature Protein
Available Sizes
Curated Selection
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