Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

PKMYT1-IN-3

PKMYT1-IN-3 (compound 8ma) is a potent and selective PKMYT1 inhibitor with an IC50 value of 16.5 nM. PKMYT1-IN-3 has antitumor activity[1].

Product Specifications

UNSPSC

12352005

Target

Wee1

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pkmyt1-in-3.html

Smiles

CC1=CC=C(C(C)=C1C2=C(C(C(N)=O)=CC(C3=CC(N4CC[C@H](C4)N)=NC(F)=C3)=C2)N)O

Molecular Formula

C24H26FN5O2

Molecular Weight

435.49

References & Citations

[1]Wang C, et al. Structure-Based Drug Design of 2-Amino-[1,1'-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of CCNE1-Amplified Breast Cancer. J Med Chem. 2024 Sep 12;67 (17) :15816-15836.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PKMYT1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

DR4 (Death Receptor 4, Apo2, CD261, CD261 Antigen, Cytotoxic Ligand TRAIL Receptor, Cytotoxic TRAIL Receptor, MGC9365, T10A, TNF Related Apoptosis Inducing Ligand Receptor 1, TRAIL Receptor 1, TRAIL R1, TRAILR1, TRAIL-R1, TRAILR-1, Tumor Necrosis Factor Receptor Superfamily Member 10a, TNFRSF10A) (FITC)
126013-FITC 100 µL

DR4 (Death Receptor 4, Apo2, CD261, CD261 Antigen, Cytotoxic Ligand TRAIL Receptor, Cytotoxic TRAIL Receptor, MGC9365, T10A, TNF Related Apoptosis Inducing Ligand Receptor 1, TRAIL Receptor 1, TRAIL R1, TRAILR1, TRAIL-R1, TRAILR-1, Tumor Necrosis Factor Receptor Superfamily Member 10a, TNFRSF10A) (FITC)

Ask
View Details
Kadsulignan J
TBZ1516 unit

Kadsulignan J

Ask
View Details
Lentiviral mouse Fam229a shRNA (UAS) - Lentiviral mouse Fam229a shRNA (UAS) (25)
GTR15148481 1 Vial

Lentiviral mouse Fam229a shRNA (UAS) - Lentiviral mouse Fam229a shRNA (UAS) (25)

Ask
View Details
CD274 (B7-h1 Protein, B7-H1, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1) (MaxLight 650)
C2549-22C-ML650 100 µL

CD274 (B7-h1 Protein, B7-H1, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1) (MaxLight 650)

Ask
View Details