QM-FN-SO3
QM-FN-SO3 is a BBB-penetrable near-infrared (NIR) aggregation-induced emission (AIE) -active probe for Aβ plaques. QM-FN-SO3 can be used for in vivo detection of Aβ plaques. QM-FN-SO3 has ultra-high S/N ratio, binding affinity, and high-performance NIR emission[1].
Product Specifications
CAS Number
2316820-94-5
UNSPSC
12171500
Target
Amyloid-β; Fluorescent Dye
Type
Dye Reagents
Related Pathways
Neuronal Signaling; Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/qm-fn-so3.html
Solubility
10 mM in DMSO
Smiles
N#C/C(C#N)=C1C=C(N(CCCS(=O)(O[Na])=O)C2=C\1C=CC=C2)/C=C/C3=CC=C(C4=CC=C(N(C)C)C=C4)S3
Molecular Formula
C29H25N4NaO3S2
Molecular Weight
564.65
References & Citations
[1]Wei Fu, et al. Rational Design of Near-Infrared Aggregation-Induced-Emission-Active Probes: In Situ Mapping of Amyloid-β Plaques with Ultrasensitivity and High-Fidelity. J Am Chem Soc. 2019 Feb 20;141 (7) :3171-3177.|[2]Wei Fu, Wei-Hong Zhu, et al. Rational Design of Near-Infrared Aggregation-Induced-Emission-Active Probes: In Situ Mapping of Amyloid-β Plaques with Ultrasensitivity and High-Fidelity. J. Am. Chem. Soc. 2019, 141, 7, 3171–3177.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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