CLZX-205
CLZX-205 (compound C-7) is a selective inhibitor of CDK9, with the IC50 of 2.9 nM. CLZX-205 plays an important role in cancer research[1].
Product Specifications
CAS Number
3033694-01-5
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/clzx-205.html
Solubility
10 mM in DMSO
Smiles
CC(N1N=NC2=C1C=C(C3=CC=NC(NC4=CC(C(N5CCCN(CC5)C)=O)=CC=N4)=C3)C=C2)C
Molecular Formula
C26H30N8O
Molecular Weight
470.57
References & Citations
[1]Ye Zhong, et al. Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation. J Med Chem. 2024 Mar 28;67 (6) :4739-4756.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK9
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