DSTN Recombinant Rabbit Monoclonal Antibody [JE36-06]
Destrin or DSTN (also known as actin depolymerizing factor or ADF) is a protein which in humans is encoded by the DSTN gene. Destrin is a component protein in microfilaments. The product of this gene belongs to the actin-binding proteins ADF (Actin-Depolymerizing Factor)/cofilin family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
DSTN, ACTDP, DSN
Swiss Prot
P60981 Human, Q9R0P5 Mouse, Q7M0E3 Rat
Cellular Locus
Actin cytoskeleton, cortical actin cytoskeleton, cytoplasm, extracellular exosome.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within Human DSTN aa 1-100 / 165.
Isotype
IgG
Clone
JE36-06
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
HeLa cell lysate, MCF7 cell lysate, A549 cell lysate, NIH/3T3 cell lysate, C6 cell lysate, PC-12 cell lysate, human brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 19 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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