α-Bulnesene
α-Bulnesene is a novel PAF receptor antagonist with the IC50 of 17.62 μM. α-Bulnesene can be isolated from Pogostemon cablin. α-Bulnesene shows inhibitory effect on platelet-activating factor and arachidonic acid induced rabbit platelet aggregation[1].
Product Specifications
CAS Number
[3691-11-0]
UNSPSC
12352211
Target
Platelet-activating Factor Receptor (PAFR)
Type
Natural Products
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/α-bulnesene.html
Purity
94.17
Solubility
DMSO : 10 mg/mL (ultrasonic; warming)
Smiles
C[C@@H]1[C@@]2([H])C(CC1)=C(CC[C@H](C2)C(C)=C)C
Molecular Formula
C15H24
Molecular Weight
204.35
References & Citations
[1]Hsu HC, et al. Alpha-bulnesene, a novel PAF receptor antagonist isolated from Pogostemon cablin. Biochem Biophys Res Commun. 2006;345 (3) :1033-1038.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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