α-Bulnesene

α-Bulnesene is a novel PAF receptor antagonist with the IC50 of 17.62 μM. α-Bulnesene can be isolated from Pogostemon cablin. α-Bulnesene shows inhibitory effect on platelet-activating factor and arachidonic acid induced rabbit platelet aggregation[1].

Product Specifications

CAS Number

[3691-11-0]

UNSPSC

12352211

Target

Platelet-activating Factor Receptor (PAFR)

Type

Natural Products

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/α-bulnesene.html

Purity

94.17

Solubility

DMSO : 10 mg/mL (ultrasonic; warming)

Smiles

C[C@@H]1[C@@]2([H])C(CC1)=C(CC[C@H](C2)C(C)=C)C

Molecular Formula

C15H24

Molecular Weight

204.35

References & Citations

[1]Hsu HC, et al. Alpha-bulnesene, a novel PAF receptor antagonist isolated from Pogostemon cablin. Biochem Biophys Res Commun. 2006;345 (3) :1033-1038.