CD30 Ligand/TNFSF8, Rat (HEK293)
CD30 Ligand is a B cell surface antigen and a ligand for CD30 (TNFRSF8), playing an inhibitory role in CD40-mediated immunoglobulin class switching[1]. CD30 Ligand is also a a marker for Hodgkin lymphoma and related hematologic malignancies, involves in activation and functioning of the T cell-dependent immune system[2]. CD30 ligand is expressed by T and B lymphocytes, macrophages, and a variety of normal haematopoietic cells and derived tumours. CD30 ligand exerts pleiotropic effects on normal and malignant lymphoid cells, including death, differentiation, or cell division[3]. As for CD30 ligand in rat contains a transmembrane domain belonging to the tumor necrosis factor (TNF) family. CD30L Protein, Cynomolgus (HEK293, Fc) is 172 amino acids in length (Q66-D237) and is expressed in the HEK293 cells with tag free.
Product Specifications
Product Name Alternative
CD30 Ligand/TNFSF8 Protein, Rat (HEK293), Rat, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/cd30-ligand-tnfsf8-protein-rat-hek293.html
Molecular Formula
683163 (Gene_ID) M0R3V3 (Q66-D237) (Accession)
Molecular Weight
Approximately 31-35 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
References & Citations
Shipping Conditions
Dry ice.
Scientific Category
Recombinant Proteins
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