Boc3Arg

Product Specifications

UNSPSC Description

Boc 3 Arg is the tert-butyl carbamate-protected arginine. Boc 3 Arg is an efficient tag to induce degradation through directly localizing the protein to the 20S proteasome[1].

Target Antigen

Proteasome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc3arg.html

Smiles

O=C(N)[C@@H](NC(OC(C)(C)C)=O)CCCN/C(NC(OC(C)(C)C)=O)=N\C(OC(C)(C)C)=O

Molecular Weight

473.56

References & Citations

[1]Sun H, et al. Identification of Boc2Lys-Linked Ethacrynic Acid and Its Analogues As Efficient Glutathione S-Transferase Degraders. ACS Med Chem Lett. 2024 Oct 14;15(11):1852-1859.|[2]Marcus J.C. Long, et al. Inhibitor Mediated Protein Degradation. Chemistry & Biology. 2021, 19 (5): 629-637.