Boc3Arg
Product Specifications
UNSPSC Description
Boc 3 Arg is the tert-butyl carbamate-protected arginine. Boc 3 Arg is an efficient tag to induce degradation through directly localizing the protein to the 20S proteasome[1].
Target Antigen
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/boc3arg.html
Smiles
O=C(N)[C@@H](NC(OC(C)(C)C)=O)CCCN/C(NC(OC(C)(C)C)=O)=N\C(OC(C)(C)C)=O
Molecular Weight
473.56
References & Citations
[1]Sun H, et al. Identification of Boc2Lys-Linked Ethacrynic Acid and Its Analogues As Efficient Glutathione S-Transferase Degraders. ACS Med Chem Lett. 2024 Oct 14;15(11):1852-1859.|[2]Marcus J.C. Long, et al. Inhibitor Mediated Protein Degradation. Chemistry & Biology. 2021, 19 (5): 629-637.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-169351/Boc3Arg-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169351/
Clinical Information
No Development Reported
Curated Selection
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