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Nipamovir

Nipamovir is a nitroimidazole prodrug. Nipamovir shows comparable antiviral activity to SAMT-247 (HY-102077) and NS-1040 in both cellular assays and a human ex vivo model of HIV infection, along with low toxicity. Nipamovir has EC50 values of 3.64±3.28 and 3.23±2.81 μM for CEM-SS/HIV-1RF and hPBMC/HIV-192HT599, respectively[1].

Product Specifications

CAS Number

[2651908-78-8]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/nipamovir.html

Purity

98.60

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NCCC(N)=O)C1=C(SC2=C([N+]([O-])=O)N=CN2C)C=CC=C1

Molecular Formula

C14H15N5O4S

Molecular Weight

349.37

Precautions

H302, H315, H319, H335

References & Citations

[1]Marco Robello, et al. Prodrug Strategy Extends the Use of Anti-HIV Sulfanylbenzamides for Application In Vivo. ACS Pharmacol. Transl. Sci. December 14, 2023.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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