SIRT2-IN-15
SIRT2-IN-15 (compound 1) is a SIRT2 deacetylase and deamyloacylase inhibitor with IC50 7 and 37 μM, respectively[1].
Product Specifications
CAS Number
[312275-43-7]
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sirt2-in-15.html
Smiles
O=C1/C(SC2=NC3=C(N12)C=CC=C3)=C/C4=C(O)C(I)=CC(Br)=C4
Molecular Formula
C16H8BrIN2O2S
Molecular Weight
499.12
References & Citations
[1]Yang J, et al. A homogeneous time-resolved fluorescence screen to identify SIRT2 deacetylase and defatty-acylase inhibitors. PLoS One. 2024 Jun 24;19 (6) :e0305000.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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