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SIRT2-IN-15

Product Specifications

UNSPSC Description

SIRT2-IN-15 (compound 1) is a SIRT2 deacetylase and deamyloacylase inhibitor with IC50 7 and 37 μM, respectively[1].

Target Antigen

Sirtuin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Epigenetics

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/sirt2-in-15.html

Smiles

O=C1/C(SC2=NC3=C(N12)C=CC=C3)=C/C4=C(O)C(I)=CC(Br)=C4

Molecular Weight

499.12

References & Citations

[1]Yang J, et al. A homogeneous time-resolved fluorescence screen to identify SIRT2 deacetylase and defatty-acylase inhibitors. PLoS One. 2024 Jun 24;19(6):e0305000.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-159126/SIRT2-IN-15-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-159126/

Clinical Information

No Development Reported

CAS Number

312275-43-7

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