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Parecoxib (Standard)

Parecoxib (Standard) is the analytical standard of Parecoxib. This product is intended for research and analytical applications. Parecoxib (SC 69124) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762) . Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo.

Product Specifications

Product Name Alternative

SC 69124 (Standard)

UNSPSC

12352005

Target

COX; Reference Standards

Type

Reference Standards

Related Pathways

Immunology/Inflammation; Others

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/parecoxib-standard.html

Smiles

CCC(NS(=O)(C1=CC=C(C2=C(C)ON=C2C3=CC=CC=C3)C=C1)=O)=O

Molecular Formula

C19H18N2O4S

Molecular Weight

370.42

References & Citations

[1]Jun Tang, et al. Effect of parecoxib, a novel intravenous cyclooxygenase type-2 inhibitor, on the postoperative opioid requirement and quality of pain control. Anesthesiology|[2]J L Mateos, et al.[Selective inhibitors of cyclooxygenase-2 (COX-2), celecoxib and parecoxib: a systematic review]. Drugs Today (Barc) . 2010 Feb;46 Suppl A:1-25.|[3]Bo Wang, et al. Chronic administration of parecoxib exerts anxiolytic-like and memory enhancing effects and modulates synaptophysin expression in mice. BMC Anesthesiol. 2017 Nov 13;17 (1) :152.|[4]Lin-Yong Li, et al. Parecoxib inhibits glioblastoma cell proliferation, migration and invasion by upregulating miRNA-29c. Biol Open. 2017 Mar 15;6 (3) :311-316.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-17474R/Parecoxib-Standard-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-17474R/

Scientific Category

Reference Standards

CAS Number

[198470-84-7]

Available Sizes

Curated Selection

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