Ac-VAD-CHO
Product Specifications
UNSPSC Description
Ac-VAD-CHO (Ac-Val-Ala-Asp-CHO) is a pan-caspase inhibitor. Ac-VAD-CHO inhibits dissipation of MMP and cytochrome c release in hypoxia-exposed cells[1].
Target Antigen
Caspase
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ac-vad-cho.html
Solubility
10 mM in DMSO
Smiles
OC(C[C@@H](C=O)NC([C@H](C)NC([C@H](C(C)C)NC(C)=O)=O)=O)=O
Molecular Weight
329.35
References & Citations
[1]Jee-Youn Kim, et al. ROS-dependent caspase-9 activation in hypoxic cell death. FEBS Lett. 2003 Aug 14;549(1-3):94-8.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W011254/Ac-VAD-CHO-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W011254/
Clinical Information
No Development Reported
CAS Number
147837-52-3
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