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Ac-VAD-CHO

Ac-VAD-CHO (Ac-Val-Ala-Asp-CHO) is a pan-caspase inhibitor. Ac-VAD-CHO inhibits dissipation of MMP and cytochrome c release in hypoxia-exposed cells[1].

Product Specifications

CAS Number

[147837-52-3]

Product Name Alternative

Ac-Val-Ala-Asp-CHO

UNSPSC

12352209

Hazard Statement

H302-H315-H319-H335

Target

Caspase

Type

Peptides

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ac-vad-cho.html

Solubility

10 mM in DMSO

Smiles

OC(C[C@@H](C=O)NC([C@H](C)NC([C@H](C(C)C)NC(C)=O)=O)=O)=O

Molecular Formula

C14H23N3O6

Molecular Weight

329.35

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Jee-Youn Kim, et al. ROS-dependent caspase-9 activation in hypoxic cell death. FEBS Lett. 2003 Aug 14;549 (1-3) :94-8.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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