Ac-VAD-CHO
Ac-VAD-CHO (Ac-Val-Ala-Asp-CHO) is a pan-caspase inhibitor. Ac-VAD-CHO inhibits dissipation of MMP and cytochrome c release in hypoxia-exposed cells[1].
Product Specifications
CAS Number
147837-52-3
Product Name Alternative
Ac-Val-Ala-Asp-CHO
UNSPSC
12352209
Hazard Statement
H302-H315-H319-H335
Target
Caspase
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ac-vad-cho.html
Solubility
10 mM in DMSO
Smiles
OC(C[C@@H](C=O)NC([C@H](C)NC([C@H](C(C)C)NC(C)=O)=O)=O)=O
Molecular Formula
C14H23N3O6
Molecular Weight
329.35
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Jee-Youn Kim, et al. ROS-dependent caspase-9 activation in hypoxic cell death. FEBS Lett. 2003 Aug 14;549 (1-3) :94-8.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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