Piperazin-2-one

Piperazin-2-one is a piperazine ring derivative containing amide and ester carbonyl groups. As an important intermediate, Piperazin-2-one can be used for the synthesis of various active compounds[1][2][3].

Product Specifications

CAS Number

[5625-67-2]

UNSPSC

12352200

Hazard Statement

H315, H317, H319, H335

Target

Drug Intermediate

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/piperazin-2-one.html

Purity

99.97

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1NCCNC1

Molecular Formula

C4H8N2O

Molecular Weight

100.12

Precautions

H315, H317, H319, H335

References & Citations

[1]Sanchez-Cespedes J, et al. Inhibition of adenovirus replication by a trisubstituted piperazin-2-one derivative. Antiviral Res. 2014 Aug;108:65-73.|[2]Yamashita T, et al. Synthesis and opiate activity of pseudo-tetrapeptides containing chiral piperazin-2-one and piperazine derivatives. Chem Pharm Bull (Tokyo) . 1997 Dec;45 (12) :1940-4.|[3]Granik V G, Glushkov R G. Use of piperazin-2-one for the synthesis of some condensed heterocyclic compounds. Pharmaceutical Chemistry Journal, 1967, 1 (4) : 190-192.