NGFR/TNFRSF16 Antibody / p75NTR / CD271
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR) . NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P08138
Host
Mouse
Reactivity
Human
Immunogen
WM245 melanoma cells of human origin were used as the immunogen for the NGFR/TNFRSF16 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
NGFR/4919
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the NGFR/TNFRSF16 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NGFR/TNFRSF16 antibody is available for research use only.
Storage Conditions
Aliquot the NGFR/TNFRSF16 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the NGFR/TNFRSF16 antibody should be determined by the researcher.
Location
Cell surface, Cytoplasm
Image Legend
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