Phosphoglucomutase 5 Antibody / PGM5 / Aciculin
Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that belongs to the phosphoglucomutase family of phosphotransferases, which play an important role in the interconversion of glucose-1-phosphate and glucose-6-phosphate. Localized to the cell junction and expressed at high levels in smooth and cardiac muscle, Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, possibly playing a role in cytoskeletal organization and function. Aciculin exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (order BSA-free format for coating), Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
Q15124
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the Phosphoglucomutase 5 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
PGM5/3552
Applications
ELISA, WB, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Phosphoglucomutase 5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Phosphoglucomutase 5 antibody is available for research use only.
Storage Conditions
Aliquot the Phosphoglucomutase 5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Phosphoglucomutase 5 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Western blot testing of human heart tissue lysate using Phosphoglucomutase 5 antibody (clone PGM5/3552) . Predicted molecular weight ~62 kDa.
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