Recombinant Ornithine Decarboxylase Antibody / ODC1

Recognizes a 51-53kDa protein, identified as the Ornithine Decarboxylase (ODC-1) . ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Product Specifications

CAS Number

9000-83-3

Specifications

ELISA (order BSA-free format for coating), Western blot: 1-2 µg/mL

UniProt

P11926

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human protein was used as the immunogen for the recombinant Ornithine Decarboxylase antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG1 k

Clone

RODC1/487

Type

Recombinant

Applications

ELISA, WB

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the recombinant Ornithine Decarboxylase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This recombinant Ornithine Decarboxylase antibody is available for research use only.

Storage Conditions

Aliquot the recombinant Ornithine Decarboxylase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the recombinant Ornithine Decarboxylase antibody should be determined by the researcher.

Location

Cytoplasmic

Image Legend

Western blot analysis of human PC3 cell lysate using recombinant Ornithine Decarboxylase antibody (clone rODC1/487) . Predicted molecular weight ~51 kDa.