Lysozyme C Antibody / LYZ
Lysozyme is an enzyme, commonly referred to as the body s own antibiotic since it kills bacteria. Natural substrate of lysozyme is the bacterial cell wall peptidoglycan (cleaving the beta[1-4] glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine) . Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Lysozyme is synthesized predominantly in reactive histiocytes rather than in resting, unstimulated phagocytes. This antibody labels myeloid cells, histiocytes, granulocytes, macrophages and monocytes. It is helpful in the identification of myeloid or monocytic nature of acute leukemia.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P61626
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 18-147 was used as the immunogen for the Lysozyme C antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
LYZ/3944
Applications
WB, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Lysozyme C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Lysozyme C antibody is available for research use only.
Storage Conditions
Aliquot the Lysozyme C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Lysozyme C antibody should be determined by the researcher.
Location
Secreted
Image Legend
Western blot testing of human spleen tissue and HepG2 cell lysates using Lysozyme C antibody (clone LYZ/3944) . Predicted molecular weight ~17 kDa.
Documents
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