LGALS3 Antibody / Galectin 3

Galectin-3 is a member of the beta-galactosidase-binding lectin family. It is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Aberrant expression of Galectin-3 is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid.Galectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiationof benign and malignant thyroid neoplasms.Galectin-3 may also be useful in the identification of certain liver disorders.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P17931

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 150-200 from the human protein was used as the immunogen for the LGALS3 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

LGALS3/4792

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the LGALS3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This LGALS3 antibody is available for research use only.

Storage Conditions

Aliquot the LGALS3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the LGALS3 antibody should be determined by the researcher.

Location

Cytoplasm

Image Legend

IHC staining of FFPE human thyroid carcinoma with LGALS3 antibody (clone LGALS3/4792) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.