Interleukin 6 Receptor subunit beta Antibody / IL6ST / CD130
IL6ST is a signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the intracellular JAK-MAPK and JAK-STAT3 signaling pathways. [UniProt]
Product Specifications
UniProt
P40189
Host
Mouse
Immunogen
Clonality
Monoclonal
Isotype
IgG2b κ
Applications
IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Interleukin 6 Receptor subunit beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Interleukin 6 Receptor subunit beta antibody is available for research use only.
CAS Number
9007-83-4
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