HIC2 Antibody / Hypermethylated in cancer 2 protein
HIC2 (HIC ZBTB Transcriptional Repressor 2) is a Protein Coding gene. Diseases associated with HIC2 include Orofaciodigital Syndrome X and Simpson-Golabi-Behmel Syndrome, Type 1. HIC2 contains 5 C2H2-type zinc fingers and 1 BTB (POZ) domain. It belongs to the krueppel C2H2-type zinc-finger protein family, Hic subfamily and is a transcriptional repressor. It is a transcription activator of SIRT1.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (order BSA-free format for coating), Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2 µg/mL
UniProt
Q96JB3
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human HIC2protein was used as the immunogen for the HIC2 antibody.
Clonality
Monoclonal
Isotype
IgG2a
Clone
PCRP-HIC2-1B1
Applications
ELISA, FACS, IF
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the HIC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This HIC2 antibody is available for research use only.
Storage Conditions
Aliquot the HIC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the HIC2 antibody should be determined by the researcher.
Image Legend
Immunofluorescent staining of PFA-fixed human HeLa cells using HIC2 antibody (green, clone PCRP-HIC2-1B1) and phalloidin (red) .
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