IL-7 Antibody
Interleukin-7 (IL-7) was originally described as a factor capable of inducing in vitro proliferation of pre-B cells from marrow cultures. The IL-7 gene encodes a protein 177 amino acids in length. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells, thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor specific chain and the IL-2 receptor chain common to the IL-2, IL-4, IL-7, IL-9 and IL-15 receptors. IL-7 stimulation leads to the activation of Janus tyrosine kinase family members JAK1 and JAK3. Other studies have shown that in T cells, the IL-7 receptor-specific chain associates with the Src kinases family Lck and Fyn. IL-7 induces phosphorylation of Insulin receptor substrate-1 (IRS-1) and Insulin receptor substrate-2 (IRS-2), originally called 4PS.
Product Specifications
UniProt
P13232
Host
Mouse
Immunogen
A portion of amino acids 27-177 was used as the immunogen for the IL-7 antibody.
Clonality
Monoclonal
Isotype
IgG1 κ
Applications
FACS, IF, IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the IL-7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IL-7 antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/51595523/datasheet/v9628-100ug.pdf
CAS Number
9007-83-4
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
S100A1 (S100 Calcium-binding Protein A1, Protein S100-A1, S-100 Protein alpha Chain, S-100 Protein Subunit alpha, S100 Calcium-binding Protein A1, S100A) (Biotin)
S100A1 (S100 Calcium-binding Protein A1, Protein S100-A1, S-100 Protein alpha Chain, S-100 Protein Subunit alpha, S100 Calcium-binding Protein A1, S100A) (Biotin)
