Angiotensin Converting Enzyme Antibody / ACE
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (order BSA-free format for coating), Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P12821
Host
Mouse
Reactivity
Human
Immunogen
Full-length recombinant human protein was used as the immunogen for the Angiotensin Converting Enzyme antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
ACE/3764
Applications
ELISA, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Angiotensin Converting Enzyme antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Angiotensin Converting Enzyme antibody is available for research use only.
Storage Conditions
Aliquot the Angiotensin Converting Enzyme antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Angiotensin Converting Enzyme antibody should be determined by the researcher.
Location
Cell Surface
Image Legend
Frequently Asked Questions
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