KLF12 Antibody
Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. KLF12 is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2 µg/mL
UniProt
Q9Y4X4
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the KLF12 antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
PCRP-KLF12-1E3
Applications
FACS, IF
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the KLF12 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This KLF12 antibody is available for research use only.
Storage Conditions
Aliquot the KLF12 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the KLF12 antibody should be determined by the researcher.
Location
Nucleus, cytoplasm
Image Legend
Immunofluorescent staining of PFA-fixed human HeLa cells using KLF12 antibody (green, clone PCRP-KLF12-1E3) and Phalloidin (red) .
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