Alpha Fodrin Antibody / Alpha II Spectrin / SPTAN1 / NEAS

Spectrin, an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane, is essential in determining the properties of the membrane including its shape and deformability. Spectrins function as membrane organizers and stabilizers, composed of nonhomologous II, a neuronal cytoskeleton protein.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

Q13813

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids2351-2475 was used as the immunogen for the Alpha Fodrin antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

SPTAN1/3506

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the Alpha Fodrin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Alpha Fodrin antibody is available for research use only.

Storage Conditions

Aliquot the Alpha Fodrin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the Alpha Fodrin antibody should be determined by the researcher.

Location

Cytoplasm

Image Legend

IHC staining of FFPE human renal cell carcinoma tissue with Alpha Fodrin antibody (clone SPTAN1/3506) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.