Monocyte Chemotactic Protein 2 Antibody / MCP2 / CCL8
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P80075
Host
Mouse
Reactivity
Human
Immunogen
A portin of amino acids 1-99 from the human protein was used as the immunogen for the Monocyte Chemotactic Protein 2 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
CCL8/3686
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Monocyte Chemotactic Protein 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Monocyte Chemotactic Protein 2 antibody is available for research use only.
Storage Conditions
Aliquot the Monocyte Chemotactic Protein 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Monocyte Chemotactic Protein 2 antibody should be determined by the researcher.
Location
Secreted
Image Legend
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