Monocyte Chemotactic Protein 2 Antibody / MCP2 / CCL8

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL

UniProt

P80075

Host

Mouse

Reactivity

Human

Immunogen

A portin of amino acids 1-99 from the human protein was used as the immunogen for the Monocyte Chemotactic Protein 2 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

CCL8/3686

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the Monocyte Chemotactic Protein 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Monocyte Chemotactic Protein 2 antibody is available for research use only.

Storage Conditions

Aliquot the Monocyte Chemotactic Protein 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the Monocyte Chemotactic Protein 2 antibody should be determined by the researcher.

Location

Secreted

Image Legend

IHC staining of FFPE human adrenal gland with Monocyte Chemotactic Protein 2 antibody (clone CCL8/3686) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.