Recombinant CD21 Antibody
CD21 also known as complement C3d receptor, Epstein-Barr virus receptor, and complement receptor type 2 (CR2), is a protein that in humans is encoded by the CR2 gene. This protein is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells have CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and maturation.It is expressed by follicular dendritic cells (FDC) and mature B cells, as well as by several types of epithelial cells. CD21 is useful in the identification of follicular dendritic cell matrix found in normal lymph node and tonsillar tissue, and also useful in identifying abnormal.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P20023
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 933-C terminal of CD21 protein was used as the immunogen for the recombinant CD21 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG
Clone
CR2/3990R
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the recombinant CD21 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant CD21 antibody is available for research use only.
Storage Conditions
Aliquot the recombinant CD21 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant CD21 antibody should be determined by the researcher.
Location
Cell Surface
Image Legend
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