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GLIS3 Antibody / GLIS family zinc finger 3 / ZNF515

Selected Variant

V9531SAF-100UG

Size: 100 µg

GLIS3 is a member of the GLI similar zinc finger protein family, and encodes a nuclear protein with five C2H2 type zinc finger domains. It functions as both an activator and repressor of transcription, and is specifically involved in the development of pancreatic beta cells, thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH) . Alternatively spliced variants that encode different protein isoforms have been described but the full length nature of only two have been determined.

Product Specifications

CAS Number

9007-83-4

Specifications

ELISA (order BSA-free format for coating), Flow cytometry: 1-2ug/million cells

UniProt

Q8NEA6

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human protein was used as the immunogen for the GLIS3 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

PCRP-GLIS3-1B11

Applications

ELISA, FACS

Purity

Protein A/G affinity

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Aliquot the GLIS3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This GLIS3 antibody is available for research use only.

Storage Conditions

Aliquot the GLIS3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the GLIS3 antibody should be determined by the researcher.

Location

Nucleus

Image Legend

FACS staining of PFA-fixed human HeLa cells with GLIS3 antibody (blue, clone PCRP-GLIS3-1B11) and isotype control (red) .

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