Alpha-2-M Antibody / Alpha-2-Macroglobulin / A2M
A2-Macroglobulin acts as an antiprotease and is able to inactivate an enormous variety of proteinases. It functions as an inhibitor of fibrinolysis by inhibiting plasmin and kallikrein. It functions as an inhibitor of coagulation by inhibiting thrombin. A2-macroglobulin may act as a carrier protein because it also binds to numerous growth factors and cytokines, such as platelet-derived growth factor, basic fibroblast growth factor, TGF-b, insulin, and IL-1b. [UniProt]
Product Specifications
UniProt
P01023
Host
Mouse
Immunogen
A portin of amino acids 604-748 from the human protein was used as the immunogen for the Alpha-2-M antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Applications
IHC-P
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the Alpha-2-M antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Alpha-2-M antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/51595063/datasheet/v9469saf-100ug.pdf
CAS Number
9007-83-4
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