HTRPA1-IN-1
HTRPA1-IN-1 (19), a norsesterterpenoid that can be isolated from the Marine Sponge Diacarnus spinipoculum, is an inhibitor of transient receptor potential Ankyrin 1 (TRPA1), with an IC50 of 2 μM[1].
Product Specifications
UNSPSC
12352005
Target
TRP Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/htrpa1-in-1.html
Solubility
10 mM in DMSO
Smiles
C[C@]1(CC[C@@]2([C@H](CC[C@@]3(C)[C@@]2([H])CCCC3=C)C)C)CC[C@@H](OO1)[C@H](C(O)=O)C
Molecular Formula
C24H40O4
Molecular Weight
392.57
References & Citations
[1]Yeonwoo Cho, et al. Norterpene Cyclic Peroxides from the Marine Sponge Diacarnus spinipoculum, Inhibitors of Transient Receptor Potential Ankyrin 1. J Nat Prod. 2024 Feb 23;87 (2) :358-364.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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