SB-216
Product Specifications
UNSPSC Description
SB-216 is a potent tubulin polymerization inhibitor. SB-216 shows strong antiproliferative potency in a panel of human cancer cell lines, including melanoma, lung cancer, and breast cancer. SB-216 can be used for cancer research[1].
Target Antigen
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sb-216.html
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C1NC2=C(C=CC(OC)=C2)N(C3=C(CCC4)C4=NC(C)=N3)C1
Molecular Weight
310.35
References & Citations
[1]Souvik Banerjee, et al. X-ray Crystallography-Guided Design, Antitumor Efficacy, and QSAR Analysis of Metabolically Stable Cyclopenta-Pyrimidinyl Dihydroquinoxalinone as a Potent Tubulin Polymerization Inhibitor. J Med Chem. 2021 Sep 9;64(17):13072-13095.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144898/SB-216-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144898/SB-216-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2756818-39-8
Available Sizes
Curated Selection
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