Resistin Antibody / RETN
The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to Insulin) also known as ADSF, is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like alpha is a secreted protein that has restricted tissue distribution and is most highly expressed in adipose tissue. Another family member, resistin-like beta, is a secreted protein expressed only in the gastrointestinal tract, particularly in the colon, in both mouse and human. Resistin-like beta expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL
UniProt
Q9HD89
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment of human RETN protein (within amino acids 19-108) was used as the immunogen for the Resistin antibody.
Clonality
Monoclonal
Isotype
IgG2 λ
Clone
RETN/4325
Applications
IHC-P, WB
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Resistin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Resistin antibody is available for research use only.
Storage Conditions
Aliquot the Resistin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Resistin antibody should be determined by the researcher.
Location
Secreted
Image Legend
Frequently Asked Questions
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