ZNF804A Antibody / Zinc finger protein 804A
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF804A (zinc-finger protein 804A) is a 1,209 amino acid protein that contains one C2H2-type zinc finger. ZNF804A interacts with Ataxin-1, a protein that is involved in RNA metabolism. The gene encoding ZNF804A maps to human chromosome 2, which consists of 237 million bases and encodes over 1,400 genes, making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
Q7Z570
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length human ZNF804A protein was used as the immunogen for the ZNF804A antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
ZNF804A/8945
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the ZNF804A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ZNF804A antibody is available for research use only.
Storage Conditions
Aliquot the ZNF804A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the ZNF804A antibody should be determined by the researcher.
Location
Nucleus
Image Legend
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