Recombinant TRIM29 Antibody / Tripartite motif-containing protein 29
Tripartite motif-containing protein 29 (TRIM29) interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
Q14134
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant fragment (within amino acids 1-200) of human TRIM29 protein was used as the immunogen for the recombinant TRIM29 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
TRIM29/9256R
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the recombinant TRIM29 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant TRIM29 antibody is available for research use only.
Storage Conditions
Aliquot the recombinant TRIM29 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the recombinant TRIM29 antibody should be determined by the researcher.
Location
Cytoplasm, Cell membrane
Image Legend
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