ARK1C1 Antibody / Aldo-keto Reductase Family 1 Member C1
DDH / AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.
Product Specifications
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL
UniProt
Q04828
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human full-length AKR1C1 protein was used as the immunogen for the ARK1C1 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
AKR1C1/9319
Applications
IHC-P, WB
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the ARK1C1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ARK1C1 antibody is available for research use only.
Storage Conditions
Aliquot the ARK1C1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.nsjbio.com/tds-pdf/ark1c1-antibody-aldo-keto-reductase-family-1-member-c1-akr1c19319-v5588
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the ARK1C1 antibody should be determined by the researcher.
CAS Number
9007-83-4
Location
Cytoplasm
Image Legend
Western blot testing of human HepG2 cell lysate using AKR1C1 antibody (clone AKR1C1/9319) . Predicted molecular weight ~37 kDa.
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