ARK1C1 Antibody / Aldo-keto Reductase Family 1 Member C1
DDH / AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL
UniProt
Q04828
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human full-length AKR1C1 protein was used as the immunogen for the ARK1C1 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
AKR1C1/9063
Applications
IHC-P, WB
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the ARK1C1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ARK1C1 antibody is available for research use only.
Storage Conditions
Aliquot the ARK1C1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the ARK1C1 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Western blot testing of human liver tissue lysate using AKR1C1 antibody (clone AKR1C1/9063) . Predicted molecular weight ~37 kDa.
Frequently Asked Questions
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