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ARK1C1 Antibody / Aldo-keto Reductase Family 1 Member C1

Selected Variant

V5581SAF-100UG

Size: 100 µg

DDH / AKR1C1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL

UniProt

Q04828

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human full-length AKR1C1 protein was used as the immunogen for the ARK1C1 antibody.

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

AKR1C1/9062

Applications

IHC-P, WB

Purity

Protein A/G affinity

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Aliquot the ARK1C1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This ARK1C1 antibody is available for research use only.

Storage Conditions

Aliquot the ARK1C1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the ARK1C1 antibody should be determined by the researcher.

Location

Cytoplasm

Image Legend

IHC staining of FFPE human liver tissue with ARK1C1 antibody (clone AKR1C1/9062) . Inset: PBS used in place of primary Ab (secondary Ab negative control) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

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