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Recombinant CD147 Antibody / Emmprin / Basigin

CD147 is expressed more intensely on thymocytes than on mature peripheral blood T cells. It is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Product Specifications

CAS Number

9000-83-3

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL, Western blot: 2-4 µg/mL

UniProt

P35613

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant fragment (within amino acids 100-300) of human BSG protein was used as the immunogen for the recombinant CD147 antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

BSG/9290R

Type

Recombinant

Applications

ELISA, IHC-P, WB

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the recombinant CD147 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This recombinant CD147 antibody is available for research use only.

Storage Conditions

Aliquot the recombinant CD147 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the recombinant CD147 antibody should be determined by the researcher.

Location

Cell membrane

Image Legend

Western blot testing of human HeLa cell lysate with recombinant CD147 antibody (clone BSG/9290R) . Expected molecular weight: 27-66 kDa depending on level of glycosylation.

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